Publications

2023

  • Crouch EE, Diafos LN, Valenzuela EJ, Wedderburn-Pugh K, Birrueta JO, Caston J, Joseph T, Andrews MG, Bhaduri A, Huang EJ. Profiling human brain vascular cells using single-cell transcriptomics and organoids. Nat Protoc. 2023 Dec 15. doi: 10.1038/s41596-023-00929-1. Epub ahead of print. PMID: 38102365. Link. 
  • Crouch EE, Damas C, Bartrug WC, Shamiyeh A, Scelfo M, Dreyfus M, Gano D, Segal S, Franck LS. Parents' Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death. JAMA Netw Open. 2023 Nov 1;6(11):e2341533. doi: 10.1001/jamanetworkopen.2023.41533. PMID: 37930699; PMCID: PMC10628732. PMC free article here. Also, UCSF Pediatrics discussed our compelling findings in their blog. 
  • Andrews MG, Siebert C, Wang L, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang E, Bhaduri A, Kriegstein AR. LIF signaling regulates outer radial glial to interneuron fate during human cortical development. Cell Stem Cell. 2023 Oct 5;30(10):1382-1391.e5. doi: 10.1016/j.stem.2023.08.009. Epub 2023 Sep 5. PMID: 37673072; PMCID: PMC10591955. Link. 
  • Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy. bioRxiv [Preprint]. 2023 Jul 11:2023.07.10.548456. doi: 10.1101/2023.07.10.548456. PMID: 37503127; PMCID: PMC10369862. Link. 
  • Jain S, Spadafora R, Maxwell S, Botas C, Nawaytou H, von Scheven E, Crouch EE. A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus. Pediatr Cardiol. 2023 Mar;44(3):736-739. doi: 10.1007/s00246-022-03056-y. Epub 2022 Dec 2. PMID: 36460799; PMCID: PMC9950208. Link. 
  • Crouch EE, Joseph T, Marsan E, Huang EJ. Disentangling brain vasculature in neurogenesis and neurodegeneration using single-cell transcriptomics. Trends Neurosci. 2023 Jul;46(7):551-565. doi: 10.1016/j.tins.2023.04.007. Epub 2023 May 18. PMID: 37210315. CellPress open access, available here. Also selected for cover which can be viewed here. 

2022

  • Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ. Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. Cell. 2022 Sep 29;185(20):3753-3769.e18. doi: 10.1016/j.cell.2022.09.004. PMID: 36179668. Free pubmed article, linked here. Also see preview by Dr. Ryann Fame here. 
  • Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME. Developmental dynamics of RNA translation in the human brain. Nat Neurosci. 2022 Sep 28. doi: 10.1038/s41593-022-01164-9. Epub ahead of print. PMID: 36171426. Link. 
  • Individual human cortical progenitors can produce excitatory and inhibitory neurons. Delgado RN, Allen DE, Keefe MG, Mancia Leon WR, Ziffra RS, Crouch EE, Alvarez-Buylla A, Nowakowski TJ. Nature. 2022 Jan;601(7893):397-403. Link.
  • Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR. Tropism of SARS-CoV-2 for human cortical astrocytes. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122236119. doi: 10.1073/pnas.2122236119. Epub 2022 Jul 12. PMID: 35858406; PMCID: PMC9335272. Link.

2020

  • Ross JM, Kim C, Allen D, Crouch EE, Narsinh K, Cooke DL, Abla AA, Nowakowski TJ, Winkler EA. The Expanding Cell Diversity of the Brain Vasculature. Front Physiol. 2020 Dec 3;11:600767. PMID: 33343397. Link. 
  • Di Marco B, Crouch EE, Shah B, Paredes M, de Almodovar C, Huang EJ, Alfonso J. A negative feedback mechanism between vascular filopodia and neural stem cells controls neurogenesis in the ventral telencephalon. Cell Reports 2020 Oct 13;33(2):108256. Link. 
  • Khakipoor S, Crouch EE, Mayer S. Current advances in modelling human cortical development – a comparative view.  Brain Research 2020 Mar 30:146803. Link. 
  • Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, CadwellCR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, NowakowskiTJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AK. Outer Radial Glia-Like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. Cell Stem Cell, 2020 Jan 2;26(1):48-63.e6. Link. 

​2018

  • Crouch EE, Doetsch F. Prospective FACS isolation of endothelial cells and pericytes from brain micro-regions. Nature Protocols 2018 Apr;13(4):738-751. Link. 

​2015

  • Crouch EE, Liu C, Silva-Vargas V, Doetsch F. Regional and Stage-Specific Effects of Prospectively Purified Vascular Cells on the Adult V-SVZ Neural Stem Cell Lineage. J Neurosci. 2015 March 18;35(11):4528-39. Link. 

Prior to 2015

  • Leduc CA, Crouch EE, Wilson A, Lefkowitch J, Wamelink MM, Jakobs C, Salomons GS, Sun X, Shen Y, Chung WK. Novel association of early onset hepatocellular carcinoma with transaldolase deficiency. JIMD Rep. 2014;12:121-7. Link. 
  • Silva-Vargas V, Crouch EE, Doetsch F. Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging. Curr Opin Neurobiol. 2013 Dec;23(6):935-42. Link. 
  • Crouch EE, Li Z, Takizawa M, Fichtner-Feigl S, Gourzi P, Montaño C, Feigenbaum L, Wilson P, Janz S, Papavasiliou FN, Casellas R. Regulation of AID expression in the immune response. J Exp Med. 2007 May 14;204(5):1145-56. Link. 
  • Kruhlak M, Crouch EE, Orlov M, Montaño C, Gorski SA, Nussenzweig A, Misteli T, Phair RD, Casellas R. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature. 2007 Jun 7;447(7145):730-4. Link.